The Medicube Retinol NMN Boosting Serum is an advanced anti-ageing serum that pairs 99.8% purity patented retinol-some at 1.9% concentration with 99% purity NMN (nicotinamide mononucleotide) to visibly firm, smooth and plump skin — without the irritation typically associated with retinol. Powered by a 5-Synergy Complex of peptides, ceramides, fermented probiotics, beta-glucan and antioxidants, this is a high-performance yet gentle serum suited to sensitive and acne-prone skin types.
Key Benefits
- Targets fine lines and wrinkles using 99.8% purity patented retinol-some at 1.9% concentration
- Firms and tightens the appearance of enlarged pores for a smoother, more refined complexion
- Boosts surface hydration with NMN, hyaluronic acid, panthenol and squalane for a plumper, glassier finish
- Clinically tested to improve the appearance of smile lines by 11% and pore-area firmness by 2.8% after two weeks of use
- Formulated with low-irritation technology — non-comedogenic and sensitivity-tested for acne-prone and sensitive skin
- Probiotic ferments (bifida ferment lysate, lactobacillus ferment lysate) soothe and support the skin microbiome
- Free from fragrance, parabens, sulfates, silicones and harsh alcohols
Suitable For
- All skin types including sensitive, acne-prone, oily, dry and combination skin
- Those concerned with fine lines, wrinkles, loss of firmness or enlarged pores
- Anyone seeking a clinically backed retinol serum with a gentler, low-irritation approach
- Not suitable for use during pregnancy
How to Use
- Apply in the serum step of your evening skincare routine, after cleansing and toning
- Weeks 1–2 (adjustment period): use 1–2 drops on targeted areas 2–3 times per week
- After adjustment: gradually increase frequency based on your skin's tolerance
- Follow with your regular moisturiser
- Always apply SPF the following morning — retinol increases sun sensitivity
- Avoid layering with AHA, BHA or vitamin C in the same routine to prevent irritation
- Patch test recommended before first use
- Store away from direct sunlight and high temperatures; use within 6 months of opening
Key Ingredients
- Retinol-some 1.9% (99.8% purity) — A patented retinol encapsulation technology that delivers vitamin A deeper into skin with reduced irritation, targeting fine lines, wrinkles, uneven texture and enlarged pores
- NMN — Nicotinamide Mononucleotide (99% purity) — A cellular energising ingredient that supports skin renewal and radiance, contributing to the serum's hydration-boosting and firming results
- Retinal (Retinaldehyde) — A potent retinoid one step closer to retinoic acid than retinol, working alongside retinol-some for enhanced anti-ageing efficacy
- Niacinamide — Brightens uneven skin tone, minimises the appearance of pores and strengthens the skin barrier
- Peptide Complex — Supports skin's structural proteins for improved firmness and elasticity
- Bifida Ferment Lysate & Lactobacillus Ferment Lysate — Probiotic ferments that calm inflammation and reinforce the skin's microbiome
- Beta-Glucan — A soothing, deeply hydrating ingredient that helps reduce redness and sensitivity
- Squalane — A lightweight emollient that locks in moisture and supports barrier function without clogging pores
- Panthenol (Pro-Vitamin B5) — Hydrates, soothes and accelerates skin repair
- Adenosine — An anti-ageing active that helps smooth the appearance of fine lines and supports skin elasticity
Full Ingredient List (INCI)
Water, Glycereth-26, Niacinamide, Glycerin, Caprylic/Capric Triglyceride, Water, Caprylic/Capric Triglyceride, Macadamia Ternifolia Seed Oil, Butylene Glycol, Hydrogenated Lecithin, Retinol, Brassica Campestris (Rapeseed) Sterols, Glycerin, 1,2-Hexanediol, Cholesterol, Polyglyceryl-10 Laurate, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Aluminum/Magnesium Hydroxide Stearate, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Potassium Cetyl Phosphate, Tris(Tetramethylhydroxypiperidinol) Citrate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Elaeis Guineensis (Palm) Oil, 1,2-Hexanediol, Cetyl Ethylhexanoate, Hydroxyacetophenone, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyacrylate Crosspolymer-6, Aluminum Starch Octenylsuccinate, Glycerin, Retinal, Squalane, Water, Polyquaternium-51, Tocopherol, Panthenol, Allantoin, Adenosine, Disodium EDTA, Water, Bifida Ferment Lysate, Lactobacillus Ferment Lysate, Lactococcus Ferment Lysate
Product Details
- Brand: Medicube
- Size: 30ml
- Skin Type: All skin types
- Fragrance-free: Yes
- Non-comedogenic: Yes
- Country of Origin: South Korea
- Delivery: Shipped in Ireland via An Post






