An advanced PDRN-enriched cream from Centellian24 — the skincare brand of Dongkook Pharmaceutical, a South Korean dermatology company with over 50 years of clinical expertise. The Expert Madeca Cream Active Renew PDRN is built around the brand's proprietary TECA-PDRN™ complex (20,000ppm), combining standardised centella asiatica TECA actives with 5D-PDRN (sourced from centella, salmon, rose, marine, and houttuynia) and Damask rose water. Alongside Sodium DNA (2,000ppm), a 10-type hyaluronic acid complex, niacinamide, glutathione, and ceramide NP, it works to visibly firm, deeply hydrate, and support barrier recovery — making it well suited to daily use and to skin that needs extra support post-treatment or during periods of sensitivity.
Key Benefits
- Visibly firms and supports the appearance of elasticity — TECA-PDRN™ complex (20,000ppm) and Sodium DNA (2,000ppm) work together to help visibly improve skin bounce and firmness with consistent use
- Deep, layered hydration — a 10-type hyaluronic acid complex (including Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, and more) delivers moisture at multiple skin depths
- Supports barrier recovery — ceramide NP, phytosphingosine, panthenol, and jojoba esters help reinforce the skin's natural lipid barrier and support resilience
- Calms and soothes sensitised skin — beta-sitosterol, centella asiatica extract, and aloe barbadensis leaf extract help visibly reduce the appearance of irritation and support skin comfort
- Visibly brightens and evens skin tone — niacinamide and glutathione work together to support a clearer, more luminous-looking complexion
- Helps visibly smooth the appearance of fine lines and wrinkles — PDRN and TECA actives support skin renewal and the appearance of a more youthful-looking surface
- Suitable for post-treatment and compromised skin — dermatology-grade formula designed to support recovery after professional skin procedures
- "Second skin" texture — elastic-hold, fast-absorbing cream that melts into skin without heaviness; comfortable under makeup
Suitable For
- All skin types, including sensitive and reactive skin
- Those looking to visibly address signs of ageing — loss of firmness, fine lines, uneven texture
- Skin requiring barrier repair or recovery support
- Post-procedure aftercare (laser, peels, microneedling)
- Anyone wanting a hydrating, calming daily moisturiser with active anti-ageing ingredients
Patch test recommended — this product contains lavender oil and bergamot fruit oil.
How to Use
- Use morning and evening as the final step of your skincare routine, after toner and serum
- Take a small amount and spread evenly across the face
- Gently pat with fingertips to aid absorption — avoid rubbing
- Follow with SPF in the morning
Tip: Can be used as a richer overnight treatment by applying a slightly more generous layer in the evening and allowing it to absorb fully before sleep.
Key Ingredients
- TECA-PDRN™ Complex (20,000ppm) — Dongkook Pharmaceutical's proprietary complex combining standardised centella asiatica TECA actives with 5D-PDRN (from centella, salmon, rose, marine, and houttuynia sources) and Damask rose water; supports the appearance of skin elasticity and renewal
- Sodium DNA / PDRN (2,000ppm) — a form of PDRN (polydeoxyribonucleotide) that supports skin repair processes and helps visibly improve the appearance of firmness and texture
- Madecassic Acid (1,600ppm), Asiaticoside & Asiatic Acid — the key TECA actives from centella asiatica; support barrier function, help calm irritation, and assist with the visible appearance of skin recovery
- 10-Type Hyaluronic Acid Complex — including Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Potassium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Dimethylsilanol Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, and Hydrolyzed Sodium Hyaluronate; delivers layered hydration at multiple depths
- Niacinamide — helps visibly brighten skin tone, support barrier function, and reduce the appearance of pores
- Glutathione — antioxidant ingredient that helps support a more visibly even, luminous complexion
- Beta-Sitosterol & Phytosterols — plant-derived calming ingredients that help reduce the appearance of irritation and support skin comfort
- Caffeine — helps visibly energise the skin's appearance and reduce puffiness
- Rosa Damascena Flower Water — Damask rose water; helps soothe and hydrate while contributing a softening skin feel
- Ceramide NP — helps reinforce the skin's natural lipid barrier to support moisture retention and resilience
Full INCI
Water, Glycerin, Dipropylene Glycol, Caprylic/Capric Triglyceride, Hydrogenated Poly (C6-14 Olefin), Glyceryl Stearate, Pentaerythrityl Tetraethylhexanoate, Niacinamide, Methyl Trimethicone, Vinyl Dimethicone, Cetearyl Alcohol, Rosa Damascena Flower Water, Polyglyceryl-10 Laurate, Sodium DNA (2,000ppm), Madecassic Acid (1,600ppm), Asiaticoside, Asiatic Acid, Centella Asiatica Extract, Glutathione, Caffeine, Beta-Sitosterol, Phytosterols, Laminaria Japonica Extract, Aloe Barbadensis Leaf Extract, Dioscorea Japonica Root Extract, Ulmus Davidiana Root Extract, Viola Mandshurica Flower Extract, Sodium Hyaluronate, Dimethylsilanol Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Dimethylsilanol, Sodium Acetylated Hyaluronate, 1,2-Hexanediol, Panthenol, C10-18 Triglycerides, Sodium Stearoyl Glutamate, Sodium Polyacryloyldimethyl Taurate, Butylene Glycol, Jojoba Esters, Glyceryl Stearate, Hydroxyacetophenone, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetyl Alcohol, Stearyl Alcohol, Behenyl Alcohol, Ceramide NP, Phytosphingosine, Lavandula Angustifolia (Lavender) Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Oil, Ethylhexylglycerin, Disodium EDTA
Product Details
- Brand: Centellian24 (by Dongkook Pharmaceutical)
- Size: 50ml
- Product type: Anti-ageing moisturising cream
- Contains fragrance: Yes (lavender oil, bergamot fruit oil) — patch test recommended
- Delivered to your door in Ireland via An Post